Blood Transfusion Research Today is a free monthly online journal that collates and summarizes the latest research about Blood Transfusion, including details on blood donation, blood types, leukemia.

The problems of indeterminate HIV results in blood transfusion services in Nigeria.

Elemuwa CO, Bassey BE, Olaleye DO

Federal Vaccine Production Laboratories, Federal Ministry of Health, Yaba, Lagos, Nigeria.

Five hundred sera samples were collected from individuals whose age range was 16-40 years, analysed using Murex 1 and 2 and Capillus HIV kit (Cambridge Biotechnology, Cambridge, UK), and confirmed with Western Blot technique (Biorad). Of these, 186 (37.2%) were repeatedly reactive, 90 (48.4%) were confirmed positive, 55 (29.6%) indeterminate (20 [10.7%] from blood donors) and 44 (22.0%) were negative. The data reveal a significant correlation between indeterminate results and confirmed positive sera (P < 0.05). This demonstrates the high incidence of indeterminate HIV results encountered in blood transfusion services.

Published 17 August 2005 in Trop Doct, 35(3): 166-7.
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