Blood Transfusion Research Today is a free monthly online journal that collates and summarizes the latest research about Blood Transfusion, including details on blood donation, blood types, leukemia. | ||||||
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Severe iron intoxication treated with exchange transfusion.Carlsson M, Cortes D, Jepsen S, Kanstrup T Pediatric Intensive Care Unit, Afdeling V, Odense University Hospital, Sdr. Boulevard 29, 5000 Odense C., Denmark. marcelacarlsson@yahoo.dk An 18-month-old previous healthy girl who had ingested 442 mg elemental iron/kg was admitted to a paediatric intensive care unit. The child was treated with gastric lavage, whole bowel irrigation and intravenous deferoxamine. After 2 h of standard therapy serum iron had risen threefold to 1362 microg/dl (244 micromol/l). The child was treated with exchange transfusion (ET; 52 ml/kg) and serum iron fell to 134 microg/dl (24 micromol/l). The patient made an uncomplicated recovery. ET should be considered in severe iron poisoning when standard therapy is inadequate. Published 21 March 2008 in Arch Dis Child, 93(4): 321-2. Articles on Blood Transfusion published 20 March 2008: Duration of red-cell storage and complications after cardiac surgery. N Engl J Med, 358(12): 1229-39. BACKGROUND: Stored red cells undergo progressive structural and functional changes over time. We tested the hypothesis that serious complications and mortality after cardiac surgery are increased when transfused red cells are stored for more than 2 weeks. METHODS: We examined data from patients given red-cell transfusions during coronary-artery bypass grafting, heart-valve surgery, or both between June 30, 1998, and January 30, 2006. A total of 2872 patients received 8802 units of blood that ... [Abstract] [Full-text] Articles on Blood Transfusion published 12 March 2008: Use of recombinant factor VIIa in massive post-partum haemorrhage. Eur J Anaesthesiol, 25(4): 293-8. BACKGROUND AND OBJECTIVE: Massive post-partum haemorrhage continues to be one of the world's leading causes of maternal morbidity and mortality. Any new treatment that potentially helps at risk parturients should be thoroughly investigated. Recombinant factor VIIa (rVIIa) is increasingly being used in the treatment of massive haemorrhage. We performed a case-matched analysis of its use since 2003 in the treatment of massive post-partum haemorrhage at our hospital. METHODS: Twenty-eight cases of ... [Abstract] [Full-text] Articles on Blood Transfusion published 7 March 2008: Non-invasive assessment of liver fibrosis by transient elastography in post transfusional iron overload. Eur J Haematol, 80(4): 337-40. BACKGROUND: Liver fibrosis, assessed by biopsy, is the main complication of post transfusional liver iron overload. Transient elastography (TE) is a new, non invasive method able to measure liver stiffness (LS) caused by fibrosis. METHOD: We prospectively evaluated the predictive value of LS measurement for liver fibrosis evaluation in 15 chronically transfused patients and compared these results with the METAVIR histological fibrosis stage from liver biopsies. RESULTS: Mean TE values ... [Abstract] [Full-text] Prognosis and postoperative lymphocyte count in patients with hepatocellular carcinoma who received intraoperative allogenic blood transfusion: a retrospective study. Eur J Surg Oncol, 34(3): 339-45. AIMS: The effect of perioperative blood transfusion on the survival of hepatocellular carcinoma (HCC) has not been fully investigated. To clarify the prognostic value of intraoperative allogenic blood transfusion, we conducted a comparative retrospective analysis of 224 patients with HCC who underwent hepatic resection. METHODS: We compared clinicopathologic background and survival after hepatic resection between patients who received intraoperative blood transfusion (n=101) and those who did ... [Abstract] [Full-text] Articles on Blood Transfusion published 4 March 2008: Efficacy of intraoperative cell saver in decreasing postoperative blood transfusions in instrumented posterior lumbar fusion patients. Spine, 33(5): 571-5. STUDY DESIGN: A retrospective study. OBJECTIVE: To determine the efficacy of using intraoperative cell saver in decreasing the need for blood transfusion. SUMMARY OF BACKGROUND DATA: Lumbar spine surgery is associated with potential large intraoperative blood loss, which may put patients at risk for blood transfusions. Preoperative autologous blood donation mitigates the need for allogenic blood transfusion, but does not eliminate it. Cell-saver use has been advocated to further reduce the need ... [Abstract] [Full-text] Articles on Blood Transfusion published 3 March 2008: Red blood cell transfusions and iron overload in the treatment of patients with myelodysplastic syndromes. Cancer, 112(5): 1089-95. BACKGROUND: Approximately 15,000 new cases of myelodysplastic syndromes (MDS) are expected in the United States each year. METHODS: The mainstay for the management of myelodysplastic syndromes (MDS) is supportive therapy with red blood cell (RBC) transfusions to improve the patient's quality of life. RBC transfusions enable adequate tissue oxygenation and increase hemoglobin levels, improve fatigue, and improve the physical and intellectual activity of patients. Up to 90% of patients with MDS ... [Abstract] [Full-text] Articles on Blood Transfusion published 27 February 2008: The effect of recombinant activated factor VII on mortality in combat-related casualties with severe trauma and massive transfusion. J Trauma, 64(2): 286-93; discussion 293-4. BACKGROUND: The majority of patients with potentially survivable combat-related injuries die from hemorrhage. Our objective was to determine whether the use of recombinant activated factor VII (rFVIIa) decreased mortality in combat casualties with severe trauma who received massive transfusions and if its use was associated with increased severe thrombotic events. METHODS: We retrospectively reviewed a database of combat casualty patients with severe trauma (Injury Severity Score [ISS] >15) ... [Abstract] [Full-text] Articles on Blood Transfusion published 26 February 2008: Assessing the potential for major trauma transfusion guidelines in the UK. Emerg Med J, 25(3): 134-5. BACKGROUND: Major trauma patients are invariably received in the emergency department by a combination of emergency department and trauma team staff. The initial assessment is largely protocol led, using Advanced Trauma Life Support (ATLS) guidelines. The task of ordering and prescribing blood products often falls to the more junior members of this team. AIM: The aim of this postal questionnaire survey was to quantify the use of transfusion guidelines for major trauma in the UK and to assess ... [Abstract] [Full-text] © 2004-2008 Blood Transfusion Research Today. All Rights Reserved. |
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